Evidence-Based Health Benefits of Papaya
The papaya is an incredibly healthy tropical fruit. It’s loaded with antioxidants that can reduce inflammation, fight disease and help keep you looking young. The papaya is a tropical fruit high in vitamins C and A, as well as fiber and healthy plant compounds. It also contains an enzyme called papain, used to tenderize meat.
Delicious and Loaded With Nutrients
Papaya is the fruit of the Carica papaya plant. It originated in Central America and Southern Mexico but is now grown in many other parts of the world.
Papaya contains an enzyme called papain, which can break down the tough protein chains found in muscle meat. Because of this, people have used papaya to tenderize meat for thousands of years.
If the papaya is ripe, it can be eaten raw. However, unripe papaya should always be cooked before eating — especially during pregnancy, as the unripe fruit is high in latex, which can stimulate contractions (1).
Papayas are shaped similar to pears and can be up to 20 inches (51 cm) long. The skin is green when unripe and orange when ripe, while the flesh is yellow, orange or red.
The fruit also has many black seeds, which are edible but bitter.
One small papaya (152 grams) contains (2):
- Calories: 59
- Carbohydrates: 15 grams
- Fiber: 3 grams
- Protein: 1 gram
- Vitamin C: 157% of the RDI
- Vitamin A: 33% of the RDI
- Folate (vitamin B9): 14% of the RDI
- Potassium: 11% of the RDI
- Trace amounts of calcium, magnesium and vitamins B1, B3, B5, E and K.
Papayas also contain healthy antioxidants known as carotenoids — particularly one type called lycopene.
What’s more, your body absorbs these beneficial antioxidants better from papayas than other fruits and vegetables (3).
Has Powerful Antioxidant Effects
Free radicals are reactive molecules created during your body’s metabolism. They can promote oxidative stress, which can lead to disease.
Antioxidants, including the carotenoids found in papayas, can neutralize free radicals (4).
Studies note that fermented papaya can reduce oxidative stress in older adults and people with prediabetes, mild hypothyroidism and liver disease (5, 6, 7, 8).
Also, many researchers believe that excessive free radicals in the brain are an important factor in Alzheimer’s disease (9).
In one study, people with Alzheimer’s given a fermented papaya extract for six months experienced a 40% drop in a biomarker which indicates oxidative damage to DNA — and is also linked to aging and cancer (10, 11).
The reduction in oxidative stress is attributed to papaya’s lycopene content and ability to remove excess iron, which is known to produce free radicals (12, 13).
Papaya has powerful antioxidant effects, which may reduce oxidative stress and lower your risk of several diseases.
Has Anticancer Properties
Research suggests that the lycopene in papaya can reduce cancer risk (12). It may also be beneficial for people who are being treated for cancer (14). Papaya may work by reducing free radicals that contribute to cancer.
Additionally, papaya may have some unique effects not shared by other fruits. Among 14 fruits and vegetables with known antioxidant properties, only papaya demonstrated anticancer activity in breast cancer cells (15).
In a small study in older adults with inflammation and precancerous stomach conditions, a fermented papaya preparation reduced oxidative damage (16). However, more research is needed before recommendations can be made.
Early research suggests that the antioxidants in papaya may reduce cancer risk and perhaps even slow cancer progression.
May Improve Heart Health
Adding more papaya to your diet may boost your heart health. Studies show that fruits high in lycopene and vitamin C may help prevent heart disease (17, 18).
The antioxidants in papaya may protect your heart and enhance the protective effects of “good” HDL cholesterol (19, 20).
In one study, people who took a fermented papaya supplement for 14 weeks had less inflammation and a better ratio of “bad” LDL to “good” HDL than people given a placebo. An improved ratio is linked to a reduced risk of heart disease (20, 21).
Papaya’s high vitamin C and lycopene content can improve heart health and may reduce your risk of heart disease.
Chronic inflammation is at the root of many diseases, and unhealthy foods and lifestyle choices can drive the inflammatory process (22).
Studies show that antioxidant-rich fruits and vegetables like papaya help reduce inflammatory markers (23, 24, 25, 26).
For example, one study noted that men who increased their intake of fruits and vegetables high in carotenoids had a significant decrease in CRP, a particular inflammatory marker (26).
Chronic inflammation is at the root of many diseases. Papayas are very high in carotenoids that can reduce inflammation.


May Improve Digestion
The papain enzyme in papaya can make protein easier to digest.
People in the tropics consider papaya to be a remedy for constipation and other symptoms of irritable bowel syndrome (IBS).
In one study, people who took a papaya-based formula for 40 days had significant improvement in constipation and bloating (27).
The seeds, leaves and roots have also been shown to treat ulcers in animals and humans (28, 29).
Papaya has been shown to improve constipation and other symptoms of IBS. The seeds and other parts of the plant have also been used to treat ulcers.
Protects Against Skin Damage
In addition to keeping your body healthy, papaya can also help your skin look more toned and youthful.
Excessive free radical activity is believed to be responsible for much of the wrinkling, sagging and other skin damage that occurs with age (30).
The vitamin C and lycopene in papaya protect your skin and may help reduce these signs of aging (31).
In one study, supplementing with lycopene for 10–12 weeks decreased skin redness after sun exposure, which is a sign of skin injury (32).
In another, older women who consumed a mixture of lycopene, vitamin C and other antioxidants for 14 weeks had a visible and measurable reduction in depth of facial wrinkles (33).
The powerful antioxidants in papaya can help your skin recover from sun damage and may defend against wrinkling.
Delicious and Versatile
Papaya has a unique taste that many people love. However, ripeness is key.
An unripe or overly ripe papaya can taste very different from a perfectly ripe one.
When optimally ripe, papaya should be yellow to orange-red in color, although a few green spots are fine. Like an avocado, its skin should yield to gentle pressure.
Its flavor is best when cold, so it’s a good idea to keep it refrigerated whenever possible.
After washing it well, you can cut it in half lengthwise, scoop out the seeds, and eat it out of the rind with a spoon, like cantaloupe or melon.
As it’s incredibly versatile, it can also be combined with other foods that complement its flavor.
Here are a few easy recipe ideas using one small papaya:
- Breakfast: Cut it in half and fill each half with Greek yogurt, then top with a few blueberries and chopped nuts.
- Appetizer: Cut it into strips and wrap a slice of ham or prosciutto around each strip.
- Salsa: Chop papaya, tomatoes, onions and cilantro, then add lime juice and mix well.
- Smoothie: Combine the diced fruit with coconut milk and ice in a blender, then blend until smooth.
- Salad: Chop papaya and avocado into cubes, add diced cooked chicken and dress with olive oil and vinegar.
- Dessert: Combine the chopped fruit with 2 tablespoons (28 grams) of chia seeds, 1 cup (240 ml) of almond milk and 1/4 teaspoon of vanilla. Mix well and refrigerate before eating.
Papaya is a delicious fruit that is best enjoyed ripe. It can be eaten alone or easily combined with other foods.
The Bottom Line
Papaya is rich in valuable nutrients and has a delicious taste.
Its powerful antioxidants like lycopene may reduce your risk of many diseases — especially ones that tend to come with age, such as heart disease and cancer.
It may also defend against the visible signs of aging, helping your skin remain smooth and youthful.
Try adding this healthy and delicious fruit to your diet today.
Health Benefits of Papaya
Nutritional Info
*Percent Daily Values are based on a 2,000 calorie diet. Your daily values may be higher or lower depending on your calorie needs.
Carica papaya is the scientific name of the orange and green fruit known more commonly as papaya. It tastes sweet and has a soft texture that many find appealing. The seeds are also edible, although they’re more bitter than the fruit itself.
Papayas are originally from Central America. They grow best in a tropical region where there is plentiful rainfall but little long-term flooding. Freezing temperatures may damage a papaya crop.
Indigenous people in the area ate papayas and used them for medicinal purposes. In the 1500s and 1600s, Spanish and Portuguese colonizers brought the seeds to other tropical areas of the globe, including the Philippines and India.
Today, Hawaii, the Philippines, India, Ceylon, Australia, and tropical regions in Africa are the most fruitful papaya-producing regions. Smaller papaya-farming operations still exist in Central and South America.
Papaya has many different names all over the globe. In Australia, it’s called a pawpaw. In southern Asia, it’s sometimes called a kepaya, lapaya, or tapaya. Its name in French is sometimes “figueir des iles,” or fig of the islands. Some Spanish names for papaya include “melon zapote,” “fruta bomba,” or “mamona.”
You may encounter many varieties of papaya in a store, including:
- Kapaho solo (also known as puna solo)
- Waimanolo
- Higgins
- Wilder
- Hortus gold
- Honey gold
- Bettina
- Improved peterson
- Sunnybank
- Guinea gold
- Coorg honeydew
- Washington
Health Benefits
Protection Against Heart Disease
Papayas contain high levels of antioxidants vitamin A, vitamin C, and vitamin E. Diets high in antioxidants may reduce the risk of heart disease. The antioxidants prevent the oxidation of cholesterol. When cholesterol oxidizes, it’s more likely to create blockages that lead to heart disease.
Additionally, papaya’s high fiber content may reduce the risk of heart disease. High-fiber diets lower cholesterol levels.
Papaya has folic acid, which is essential for converting the amino acid homocysteine into less harmful amino acids. High levels of homocysteine, an amino acid primarily found in meat products, are a risk factor for heart disease. So eating papaya in your diet may lower homocysteine levels, reducing this risk factor.
Digestion and Reduced Inflammation
The papaya fruit contains two enzymes, papain and chymopapain. Both enzymes digest proteins, meaning they can help with digestion and reduce inflammation. Papain is an ingredient in some over-the-counter digestive supplements to help with minor upset stomach.
Both papain and chymopapain also help to reduce inflammation. They may help acute pain, like those from burns or bruises, and they can help with chronic inflammatory conditions like arthritis and asthma.
Immune System
Eating foods high in vitamin C can help to boost the immune system, allowing the body to fight off bacterial and viral illnesses. Papaya has a good amount of this antioxidant, making it part of an immune-healthy diet.
Papaya is also a good source of Vitamin A, another important vitamin for a healthy and functional immune system.
Potentially Protects Against Prostate Cancer
Lycopene is a natural pigment found in foods that are red or orange. Tomatoes, watermelon, and papaya are good sources of lycopene. Some experts believe that eating more lycopene reduces the risk of prostate cancer, but some studies have been inconclusive.
However, in other studies, eating a diet high in lycopene along with green tea reduced the risk of prostate cancer significantly.
Nutrition
A medium-sized papaya contains more than 200% of the vitamin C you need per day, helping to reduce the risk of heart disease and boost the immune system. It’s also a good source of:
Nutrients per Serving
A medium-sized papaya (approximately 275 grams) contains about:
- 119 calories
- 1.3 grams of protein
- 30 grams of carbohydrates
- Less than 1 gram of fat
- 4.7 grams of dietary fiber
- 21.58 grams of sugar
Things to Watch Out For
Papaya is generally safe to consume, but some people may experience allergic reactions. Papaya has natural sugars, so if you need to avoid sugar for any reason, eat an amount that fits with your health needs.
How to Eat a Papaya
When choosing a papaya at the store, consider when and how you want to eat it. Green papayas are not ripe yet and will not have the characteristic flavor or texture. However, unripe papayas are used in some cooked dishes or raw in certain styles of salads. Papayas with red and orange skin are riper. You want it to be slightly soft to the touch, but not overly soft.
If you do buy unripened papayas, store them at room temperature to allow them to ripen before consuming.
Once you are ready to eat the papaya, simply cut it open, scoop out the seeds, and eat the orange interior. The skin and seeds are not poisonous, but most people do not eat them.
Many recipes include papaya, such as:
- Papaya salsa
- Papaya jam
- Papaya smoothies
- Papaya relish
- Fruit bowls with papaya
- Papaya salads
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